Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics: Trends in Biochemical Sciences The role of ROS in exercise mediated WAT browning. Exercise causes oxidative stress in skeletal muscle and reduces the level of GSH. GSH provides electrons for glutathione peroxidase (GPXs), which eliminates H2O2. Reducing Living on the Edge: ROS Homeostasis in Cancer Cells and Its Potential as a Therapeutic Target Frontiers Glutathione and mitochondria Heat induced longevity in budding yeast requires respiratory metabolism and glutathione recycling Figure f6 Aging